Triple negative breast cancer is hormone receptor negative (ER- and PR-) and HER2 negative, which disqualifies it from being treated with most targeted therapies and hormone therapies. This kind of cancer is usually treated with chemotherapy, sometimes in the neoadjuvant (pre-surgery) setting, although more research is needed to determine if neoadjuvant chemo actually improves response. Sometimes, triple negative breast cancer responds better to traditional chemotherapy than hormone positive breast cancer. But in general, more treatment options need to be developed for this kind of cancer.
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