Risk Factors For Uterine Cancer


  • OBESITY: Obesity can increase uterine cancer risk; uterine cancer is three times more common among obese women than those at a healthier weight.
  • AGE: Uterine cancer risk increases with age.
  • FAMILY HISTORY: If several family members have/had uterine cancer, your healthcare professional may recommend genetic testing.
  • GENETICS: Lynch syndrome is a hereditary cancer syndrome that is linked to an increase in uterine cancer. The lifetime risk of developing uterine cancer for women with Lynch syndrome is 40% to 60%.
  • NUTRITION & DIET: Diets high in fat can increase risk.
  • MENSTRUAL HISTORY: Women who begin menstruation before age 12 or reach menopause after age 55 have a higher risk.
  • REPRODUCTIVE HISTORY: Women who have never been pregnant, or those who cannot get pregnant, are at higher risk.
  • HORMONE REPLACEMENT THERAPY (HRT): Taking estrogen alone, without progestin, can increase risk.
  • TAMOXIFEN USE: Tamoxifen, which is often used to treat breast cancer, can slightly increase the risk of developing uterine cancer.

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