Stephanie Gaillard, MD PHD, Director, Gynecologic Cancer Trials and Co-Director, Developmental Therapeutics/Phase I Clinical Trials Program, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. Dr. Gaillard will explain what the No Specific Molecular Profile (NSMP) category of endometrial/uterine cancer is and tell us about the research that is going on in the various subcategories of NSMP. The NSMP molecular category includes molecular mutations that don’t fit into the three other categories: POLE Ultramutated, MS-H, Copy number high/P53 mutated. Some of the common attributes of the NSMP category are: pMMR, MS-I Stable (aka MS-S), Copy number low, ER+ PR+, HER2-, PIK3ca, KRAS, PTEN, CTNNB1, L1CAM, or others.